What We Do
The McMaster Developmental Hemostasis Lab (MDHL) works under the supervision of Dr. Anthony Chan. Our research is focused on the study of the hemostatic system in children and developing improved treatments for children with a variety of thrombotic and bleeding disorders. We also work on development of novel systemic antithrombotic medications and on improving biocompatibility of blood-contacting devices. Dr. Chan is one of the principal developers of Antithrombin-Heparin Covalent Complex (ATH), a potent pulmonary and systemic anticoagulant with potential for use in various clinical indications of thrombosis, as well as a coating for blood-contacting devices.
Who We Are
Dr. Anthony Chan is a pediatric hematologist and one of the leading experts in the field of pediatric thrombosis and stroke. Dr. Chan is a professor in the Department of Pediatrics at McMaster University and the director (pediatrics) of the Hemophilia Treatment Centre at McMaster Children’s Hospital. He holds the inaugural McMaster Children’s Hospital/Hamilton Health Sciences Foundation Chair in Pediatric Thrombosis and Hemostasis. He is involved in designing clinical trials in pediatric thrombosis and pediatric stroke, as well as providing around-the-clock free consultation worldwide through the 1-800-NOCLOTS service.
Dr. Chan was awarded the Order of Ontario in 2017 for his care of children with thrombosis and stroke.
Current Lab Members
Anthony Chan
MBBS, FRCPC, FRCPCH, FRCPI (Hon), FRCP (Glas), FRCPath
Professor,
Department of Pediatrics
Anthony Chan
MBBS, FRCPC, FRCPCH, FRCPI (Hon), FRCP (Glas), FRCPath
Professor,
Department of Pediatrics
Siyuan Li
PhD Candidate
Project: Dual surface functionalization with an antithrombin-heparin complex (ATH) and tissue plasminogen activator (t-PA) for blood contacting devices including microfluidic blood oxygenators
Department of Biomedical Engineering, co-supervised with Dr. Kyla Sask
Anthony Chan
MBBS, FRCPC, FRCPCH, FRCPI (Hon), FRCP (Glas), FRCPath
Professor,
Department of Pediatrics
Anthony Chan
MBBS, FRCPC, FRCPCH, FRCPI (Hon), FRCP (Glas), FRCPath
Professor,
Department of Pediatrics
Siyuan Li
PhD Candidate
Project: Dual surface functionalization with an antithrombin-heparin complex (ATH) and tissue plasminogen activator (t-PA) for blood contacting devices including microfluidic blood oxygenators
Department of Biomedical Engineering, co-supervised with Dr. Kyla Sask
Siyuan Li
PhD Candidate
Project: Dual surface functionalization with an antithrombin-heparin complex (ATH) and tissue plasminogen activator (t-PA) for blood contacting devices including microfluidic blood oxygenators
Department of Biomedical Engineering, co-supervised with Dr. Kyla Sask
Former Students
Wajeeha Zaheer
MSc
Wajeeha Zaheer
MSc
Paul Tieu
MSc
Paul Tieu
MSc
Karen Strike
PhD
Karen Strike
PhD
Sajjad Afraz
MSc, MD
Sajjad Afraz
MSc, MD
Laura Calvert
MSc
Laura Calvert
MSc
Gabriela Chang
MSc
Gabriela Chang
MSc
Jason Chung
MSc
Jason Chung
MSc
Jorell Gantioqui
MSc
Jorell Gantioqui
MSc
Jennifer Leung
MSc
Biomedical Engineering (co-supervised)
Jennifer Leung
MSc
Kyla Sask
PhD
Biomedical Engineering (co-supervised)
Kyla Sask
PhD
Ivan Stevic
PhD
Ivan Stevic
PhD
Ankush Chander
MSc, MD
Ankush Chander
MSc, MD
Marieke VanWalderveen
MSc
Marieke VanWalderveen
MSc
Sanjay Patel
MSc
Sanjay Patel
MSc
Wajeeha Zaheer
MSc
Wajeeha Zaheer
MSc
Paul Tieu
MSc
Paul Tieu
MSc
Karen Strike
PhD
Karen Strike
PhD
Sajjad Afraz
MSc, MD
Sajjad Afraz
MSc, MD
Laura Calvert
MSc
Laura Calvert
MSc
Gabriela Chang
MSc
Gabriela Chang
MSc
Jason Chung
MSc
Jason Chung
MSc
Jorell Gantioqui
MSc
Jorell Gantioqui
MSc
Jennifer Leung
MSc
Biomedical Engineering (co-supervised)
Jennifer Leung
MSc
Biomedical Engineering (co-supervised)
Kyla Sask
PhD
Biomedical Engineering (co-supervised)
Kyla Sask
PhD
Biomedical Engineering (co-supervised)
Ivan Stevic
PhD
Ivan Stevic
PhD
Ankush Chander
MSc, MD
Ankush Chander
MSc, MD
Marieke VanWalderveen
MSc
Marieke VanWalderveen
MSc
Sanjay Patel
MSc
Sanjay Patel
MSc