McMaster Developmental Hemostasis Lab (MDHL) - Thrombosis & Atherosclerosis Research Institute (TaARI)

What We Do

The McMaster Developmental Hemostasis Lab (MDHL) works under the supervision of Dr. Anthony Chan. Our research is focused on the study of the hemostatic system in children and developing improved treatments for children with a variety of thrombotic and bleeding disorders. We also work on development of novel systemic antithrombotic medications and on improving biocompatibility of blood-contacting devices. Dr. Chan is one of the principal developers of Antithrombin-Heparin Covalent Complex (ATH), a potent pulmonary and systemic anticoagulant with potential for use in various clinical indications of thrombosis, as well as a coating for blood-contacting devices.

Who We Are

Dr. Anthony Chan is a pediatric hematologist and one of the leading experts in the field of pediatric thrombosis and stroke. Dr. Chan is a professor in the Department of Pediatrics at McMaster University and the director (pediatrics) of the Hemophilia Treatment Centre at McMaster Children’s Hospital. He holds the inaugural McMaster Children’s Hospital/Hamilton Health Sciences Foundation Chair in Pediatric Thrombosis and Hemostasis. He is involved in designing clinical trials in pediatric thrombosis and pediatric stroke, as well as providing around-the-clock free consultation worldwide through the 1-800-NOCLOTS service.

Dr. Chan was awarded the Order of Ontario in 2017 for his care of children with thrombosis and stroke.